Jerome Groopman's Blog

When to ask, "What else could it be?"

Friday, March 30, 2007

There is no absolute solution for misdiagnosis since slowing down the medical process to test every patient for every possible condition given their symptoms is completely impractical. This is a very good point and one we need to keep in mind. The book is intended to get doctors to be conscious of how their thought processes can help or hinder a diagnosis as well as to get patients to stop and think about their role in helping the doctor come to an accurate conclusion.

Asking, “What else could it be?” is certainly not intended to be an invitation for a laundry list of probably useless tests but instead a device the patient can use to help the doctor look at the problem from all angles and perhaps put together the pieces of information in a new way. And this is not necessarily a question for a first visit, either. If there have been the same symptoms for a long time and recommended treatments have not solved the problem, then patients and doctors should start thinking about other options. This is a way to open up that avenue of dialogue.

This was written in response to a comment in a column from a National Post article in which How Doctor's Think is referenced.

Medical Education

Wednesday, March 28, 2007

Another piece in the New England Journal of Medicine that I found of interest was a series of letters about medical education. I feel strongly that it is time to integrate cognitive psychology into the curriculum. Physicians are making decisions all the time under conditions of uncertainty, with limited data. The human mind is wired to take shortcuts, and our biases and emotions can strongly color our reasoning. Scant attention is paid to this critical cognitive dimension which underlies misdiagnosis. Over the past years, many medical educators have proposed algorithms and illness scripts to medical students and residents. These are based on prototypes, typical patients with diseases that have typical symptoms and findings on physical examination or laboratory testing. As the letters in the New England Journal of Medicine articulate, such illness scripts and algorithms are very seductive, because, working under time pressure, and with incomplete data, it is much easier to follow than to lead, much easier to just grab on to the algorithm or illness script rather than take the time to think expansively. This is not to say that such algorithms are worthless. But they have to be put into context, consulted and evaluated, but not automatically adopted. As several of the medical educators write in the New England Journal of Medicine, illness scripts can paradoxically foster misdiagnosis by causing anchoring errors and premature closure.

I am heartened by the increased debate around these issues. Every misdiagnosis I made was painful – most painful, of course, for the patient, but, also for me. As physicians, we are constantly trying to do our best. We know that we are imperfect, and will always fall short of one-hundred-percent. So, we need to work in an environment that allows us to think better, and we need to be educated in self-awareness, both about our cognitive processes and how our emotional state can affect our judgment. For those interested in delving more deeply, I suggest reading the Ginsburg and Berenson article as well as the letters section of the March 22, 2007, New England Journal of Medicine.

Healthcare and Cognitive Medicine

Tuesday, March 27, 2007

There was an item in the March 22, 2007 New England Journal of Medicine that caught my eye. It was an opinion piece by Drs. Paul D. Ginsburg and Robert A. Berenson. Ginsburg is the president of the Center for Studying Health System Change in Washington, DC and Berenson is a senior consulting researcher there, as well as a senior fellow at the Urban Institute. I admit that I never fully understood how the system of payments for clinical care evolved, and the countervailing forces at play in the effort to reform healthcare. In clear and concise language, Ginsburg and Berenson explain the background and lay out what, to my mind, is one of the most glaring problems facing both physicians and patients: the undervaluation of thinking in medicine.

When you come to a doctor, he or she talks to you about your symptoms, examines you, and sits down and tries to formulate a diagnosis and explain what tests are needed and what treatments are appropriate; this aspect of practice is termed "cognitive" or "thinking" medicine, and is very poorly reimbursed by Medicare and private insurers in general. This means that physicians who practice cognitive medicine, like general practitioners, pediatricians, and internists, are pressed to see as many patients as possible in shorter periods of time in order to sustain revenue and defray overhead. On the other hand, clinical care that involves procedures, particularly surgery, or sophisticated imaging techniques, like CAT scans and MRI scans, are much more richly reimbursed. While I believe that surgeons and radiologists should be rewarded for their skills and the intensity of the treatments they deliver, it seems penny wise and pound foolish to not value cognitive medicine.

First and foremost, a correct diagnosis begins with the dialogue between patient and physician. Rushing through an appointment is a set-up for cognitive errors, particularly anchoring where you fix your mind on your first impression, and premature closure, where you shut your mind off to other possibilities. Once you miss the diagnosis, there is a real risk to the patient. In addition, for those who calculate healthcare costs, it is much more expensive to care for someone whose disease has progressed rather than having been diagnosed early. Furthermore, preventive medicine is all about communication. We have all heard, in detail, about the benefits of stopping smoking, losing weight, exercising regularly, and reducing stress in terms of heart disease, cancer, and mental health. Changing behavior is difficult, but, in my experience, most likely succeeds when there is time allotted to the discussion, a close bond between the patient and doctor, and continuing encouragement. It boils down to words and positive feelings, and the health benefits can be extraordinary. Much of what primary care physicians do involves preventive medicine. Unfortunately, the system, based on its payments, is telling us that this has meager value.

It is time to change this. As Ginsburg and Berenson point out, there are powerful lobbying forces against changing payment schedules, and even though a bone is thrown on occasion to increase payment for a certain cognitive practice, at the same time, payments are reduced for other kinds of thinking medicine. It ends up as a wash, if not a reduction in rewards for those doctors who are trying to prevent disease or make a thoughtful diagnosis that takes time. In my own specialty of blood diseases and cancer and AIDS, much time is spent talking to patients about their needs and values as they face harrowing problems. These patients seek to integrate their beliefs and values into risky choices. Such discussions take time, but they are vital, both to the physical wellbeing of the patient and his or her emotional and spiritual state. Again, this dimension of medicine seems to be discounted in the healthcare reimbursement structure.

Blog Discussions

Wednesday, March 21, 2007

Bloggers have been taking notice and it looks like word about the book is spreading. Kevin M.D. commented on this "intriguing new book" on his blog. Paul Levy, President of Beth Israel Deaconess Hospital, had some very kind words on his blog, Running a Hospital. Some other great blog comments regarding the book includes Wesley of Life Two who notes, "Most importantly gain an understanding of the process of diagnosis which is probably the single most important factor in becoming healthy," and Healthcare Economist has posted a brief excerpt from the book. Psych Central also has thoughtful and interesting commentary. All the blog feedback has been greatly appreciated; it's fantastic to see this dialogue.

Book Release

Monday, March 19, 2007

As of today, How Doctors Think is on bookshelves and available through Amazon. It's already been getting some great coverage. This is a topic that holds a lot of interest since every one of us is a patient at some point in our lives and it has sparked some very worthwhile conversations. The reception for this book has been very warm and welcoming. Take a look at the new press area to see what people have been saying! It is great to see that there is so much interest in the thought process of doctors, which is something that deserves to be given a good deal of consideration.

Also, if you happen to be watching Comedy Central tonight, check out the Colbert Report for further discussion.

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